Illuminating the dark matter of the genome

Illuminating the dark matter of the genome Nature Reviews Genetics 8, 490-491 (July 2007) doi:10.1038/nrg2139 Although much of the eukaryotic genome is transcribed, the function of most of this transcriptome remains unknown. Therefore, in a parallel to cosmology, it has been dubbed the dark matter of the genome. Kapranov et al. now shed light on its possible function by identifying new classes of RNAs that might have an important role in regulating gene transcription, and showing that many long transcripts might function as precursors for shorter RNAs. .........

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