Tuesday, 5 August 2008

Progress of China's Stem Cell Research

Impressive Scope of Chinese Stem Cell and Regenerative Medicine Research Tuesday, 05 August 2008 To get an assessment of how extensive and serious stem cell research has become in China proper, it is only to look through the proceedings from Shanghai International Symposium on Stem Cell Research, held in November 2007, and published in Cell Research (Volume 18, Issue S1, August 2008) today. The organisers write: “the topics of the representations covered: adult stem cells; embryonic stem cells; stem cell niche and regulation; reprogramming, epigenetics and cloning; directed stem cell differentiation; stem cells and diseases; global issues of stem cell research: ethics, international collaborations and publications.” Several hundreds of Chinese researchers (and Chinese born scientists from other countries) participated in the meeting, which show a truly impressive wide range and scope of the Chinese efforts in stem cell research and regenerative medicine. The symposium was co-organized by the Key Laboratory of Stem Cell Biology, Shanghai Institutes for Biological Sciences; the Chinese Academy of Sciences (CAS); Shanghai Jiaotong University School of Medicine; Fudan University; Beijing University Stem Cell Research Center; and Guangzhou Institutes of Health and BioMedicine of CAS, together with the International Society for Stem Cell Research (ISSCR). This is in stark contrast to the recently held China Stem Cell Technology Forum in Taizhou (see Stem Cell Forum in China Demonstrate Cutting Edge Research), which only tried to promote the questionable practices of Beike Biotechnology Co., Ltd.. Reference: Abstracts from 2007 Shanghai International Symposium on Stem Cell Research Cell Research Volume 18, Issue S1, August 2008 ......... ZenMaster


For more on stem cells and cloning, go to CellNEWS at http://cellnews-blog.blogspot.com/ and http://www.geocities.com/giantfideli/index.html

Extinction Threat Growing for Mankind’s Closest Relatives

Monkeys and other primates dying off due to habitat loss, hunting Tuesday, 05 August 2008 Mankind's closest relatives – the world's monkeys, apes and other primates – are disappearing from the face of the Earth, with some literally being eaten into extinction. The first comprehensive review in five years of the world's 634 kinds of primates found that almost 50 percent are in danger of going extinct, according to the criteria of the IUCN Red List of Threatened Species. Issued at the 22nd International Primatological Society Congress in Edinburgh, Scotland, the report by the world's foremost primate authorities presented a chilling indictment on the state of primates everywhere. In Asia, more than 70 percent of primates are classified on the IUCN Red List as Vulnerable, Endangered or Critically Endangered – meaning they could disappear forever in the near future. The main threats are habitat destruction, particularly from the burning and clearing of tropical forests that also emits at least 20 percent of the global greenhouse gases causing climate change, and the hunting of primates for food and an illegal wildlife trade. "We've raised concerns for years about primates being in peril, but now we have solid data to show the situation is far more severe than we imagined," said Russell A. Mittermeier, president of Conservation International (CI) and the long-time chairman of the IUCN Species Survival Commission's Primate Specialist Group. "Tropical forest destruction has always been the main cause, but now it appears that hunting is just as serious a threat in some areas, even where the habitat is still quite intact. In many places, primates are quite literally being eaten to extinction." The review funded by CI, the Margot Marsh Biodiversity Foundation, Disney's Animal Kingdom and the IUCN is part of an unprecedented examination of the state of the world's mammals to be released at the 4th IUCN World Conservation Congress in Barcelona in October. With the input of hundreds of experts worldwide, the primate review provides scientific data to show the severe threats facing animals that share virtually all DNA with humans. In both Vietnam and Cambodia, approximately 90 percent of primate species are considered at risk of extinction. Populations of gibbons, leaf monkeys, langur and other species have dwindled due to rampant habitat loss exacerbated by hunting for food and to supply the wildlife trade in traditional Chinese medicine and pets. "What is happening in Southeast Asia is terrifying," said Jean-Christophe ViĆ©, Deputy Head of the IUCN Species Program. "To have a group of animals under such a high level of threat is, quite frankly, unlike anything we have recorded among any other group of species to date." Elsewhere, species from tiny mouse lemurs to massive mountain gorillas face challenges to survive. In Africa, 11 of the 13 kinds of red colobus monkeys assessed were listed as Critically Endangered or Endangered. Two may already be extinct: Bouvier's red colobus (Procolobus pennantii bouvieri) has not been seen in 25 years, and no living Miss Waldron's red colobus (Procolobus badius waldroni) has been seen by a primatologist since 1978, despite occasional reports that some still survives. "Among the African species, the great apes such as gorillas and bonobos have always tended to grab the limelight, and even though they are deeply threatened, it is smaller primates such as the red colobus that could die out first," said IPS President Richard Wrangham. As our closest relatives, nonhuman primates are important to the health of their surrounding ecosystems. Through the dispersal of seeds and other interactions with their environments, primates help support a wide range of plant and animal life in the world's tropical forests. Healthy forests provide vital resources for local human populations, and also absorb and store carbon dioxide that causes climate change. Meanwhile, scientists continue to learn more about primates and their role in the world. Since 2000, 53 species of primates previously unknown to science have been described – 40 from Madagascar, two from Africa, three from Asia and eight from Central and South America. In 2007, researchers found a long-rumoured population of Critically Endangered greater bamboo lemurs (Prolemur simus) in a wetland 400 kilometres (240 miles) from the only other known home of the species. In total, the species numbers about 140 individuals in the wild. The IUCN Red List sets a series of criteria for a species to be categorized as threatened. In cases lacking the necessary information, the species can be listed as Data Deficient, which applied to nearly 15 percent of the primates in the new review. Many of those species, particularly newly discovered ones, are expected to eventually be classified as threatened. Despite the gloomy assessment, conservationists point to a notable success in helping targeted species recover. In Brazil, the black lion tamarin (Leontopithecus chrysopygus) was down-listed to Endangered from Critically Endangered, as was the golden lion tamarin (Leontopithecus rosalia) in 2003, as a result of three decades of conservation efforts involving numerous institutions. Populations of both animals are now well-protected but remain very small, causing an urgent need for reforestation to provide new habitat for their long-term survival. "If you have forests, you can save primates," said CI scientist Anthony Rylands, the deputy chair of the IUCN Primate Specialist Group. "The work with lion tamarins shows that conserving forest fragments and reforesting to create corridors that connect them is not only vital for primates, but offers the multiple benefits of maintaining healthy ecosystems and water supplies while reducing greenhouse gas emissions that cause climate change." Researchers also considered reclassifying the mountain gorilla (Gorilla beringei beringei) to Endangered from Critically Endangered due to increasing populations in their only habitat – the protected mountain jungles of Rwanda, Uganda and Democratic Republic of Congo. However, the slayings of eight mountain gorillas in 2007 and continuing political turmoil in the region delayed the planned reclassification. See also: Spain Give Great Apes Human Rights CellNEWS - Thursday, 26 June 2008 Should Great Apes Have Human Rights? CellNEWS - Thursday, 26 June 2008 ......... ZenMaster


For more on stem cells and cloning, go to CellNEWS at http://cellnews-blog.blogspot.com/ and http://www.geocities.com/giantfideli/index.html

Monday, 4 August 2008

For Sale: Bodies, Parts, Eggs, Genes, Stem Cells

For sale: Bodies, parts, eggs, genes, stem cells Monday, 04 August 2008 Author: Donna Dickenson In the 1960s, feminists coined the slogan, "Our bodies, our selves." But that liberating sentiment has recently undergone an ironic twist. As an anonymous American woman, justifying her decision to undergo cosmetic surgery, put it, "All we have in life is ourselves, and what we can put out there every day for the world to see ... Me is all I got." The French commentator Herve Juvin extolled this new attitude towards the body in his 2005 surprise bestseller, "Lavenement du Corps" ("The Coming of the Body"). Plastic surgery, the implantation of biochips, piercings — all emblazon the belief that our bodies are our unique property. At the same time, Juvin asserts, because everyone has a body, property has suddenly become democratized. We appear to live in a time that has witnessed the absolute failure of the grand Enlightenment dreams of linear progress, universal peace, and equality between rich and poor. Together with widespread hostility to organized religion, manifested in such hugely popular books as Richard Dawkins's "The God Delusion," disappointment with social ideals means that we turn inward. In the absence of a belief in eternal life, everything becomes invested in this life, this body. Long life is our desire, eternal youth our supposed right, and the myth of the body without origin or limits our new religion. That might be why governments are so widely seen to have a positive duty to promote stem cell research and other forms of medical progress. Biotechnology industries flourish, with state sanction and support, because they add extra value to the body, the object of supreme worth to us. Indeed, the infinite renewal of the body isn't confined to superficial repairs through cosmetic surgery. External substitutes for organic structures can be surgically implanted, breaking down the barrier between the body and the outside world. At the same time, tissue removed from the body enters into commerce and trade as a commodity like any other, in the form of stem cell lines, human eggs, and other "products." The American law professor James Boyle believes that we can grasp the way in which the body has become an object of trade by likening it to the historical process of enclosure. In 18th-century Britain, land, which was previously a public resource, was "enclosed" by private owners. Freed of feudal-style legal restrictions on transfer of ownership and of traditional rights held by commoners who used communal land to pasture their animals, landholdings could now be sold to raise capital, which helped to finance the industrial revolution. In modern biotechnology, Boyle thinks, things previously outside the market — once thought to be impossible to commodify — are becoming routinely privatized. One in five human genes is now patented, even though the human genome might be thought to be our common heritage. And although Boyle doesn't mention this latest development, umbilical cord blood, taken in the final stage of labour, is now banked by profit-making firms as a potential — though unlikely — source of stem cells for the baby. In biomedicine, a series of legal cases have generated powerful momentum toward the transfer of rights over the body and its component parts from the individual "owner" to corporations and research institutions. So the body has entered the market, becoming capital, just as land did, though not everyone benefits, any more than the dispossessed commoners grew wealthy during the agricultural enclosures. Most people are shocked when they learn that one-fifth of the human genome has been patented, mostly by private firms. But why be so surprised? After all, female bodies have been subject to various forms of property-holding over many centuries and in many societies. Women's bodies are used to sell everything from cars to pop music, of course. But female tissue has been objectified and commodified in much more profound ways, in legal systems from Athens onwards. While men were also made into objects of ownership and trade, as slaves, in general women were much more likely to be treated as commodities in non-slave-owning systems. Once a woman had given her initial consent to the marriage "contract," she had no right to retract her consent to sexual relations — ever. There are clear parallels between that situation and the way in which the common law has offered little redress to patients who have tried to claim property rights in tissue taken from them. About the source: The author, Donna Dickenson, is Emeritus professor of Medical Ethics and Humanities at the University of London, was the 2006 winner of the International Spinoza Lens Award for contribution to public debate on ethics. Copyright: Project Syndicate/Institute for Human Sciences, 2008. www.project-syndicate.org ......... ZenMaster


For more on stem cells and cloning, go to CellNEWS at http://cellnews-blog.blogspot.com/ and http://www.geocities.com/giantfideli/index.html