tag:blogger.com,1999:blog-4773006751705542199.post2418065526543294213..comments2023-09-08T16:37:12.053+02:00Comments on CellNEWS: Human Embryonic Stem Cells: A New Model for Lou Gehrig's DiseaseZenMasterhttp://www.blogger.com/profile/10552303865803940754noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-4773006751705542199.post-17584741098048014682009-02-25T02:23:00.000+01:002009-02-25T02:23:00.000+01:00They transfected the cells with various mutant for...They transfected the cells with various mutant forms of SOD-1 gene (superoxide dismutase 1). This is not a signalling molecule, but is known to be linked to familial amyotrophic lateral sclerosis (ALS). You can read more in the article above. <BR/><BR/>ZenMasterZenMasterhttps://www.blogger.com/profile/10552303865803940754noreply@blogger.comtag:blogger.com,1999:blog-4773006751705542199.post-13142881898286350612009-02-25T01:53:00.000+01:002009-02-25T01:53:00.000+01:00How are the stem cells "engineered" to mimic inher...How are the stem cells "engineered" to mimic inherited ALS. Are they inducing a signal transduction pathway? This potential treatment could potentially reach far beyond Lou Gehrig's Disease. I am also curious of what the side effects have been of the animal models with limited success. I would be curious to see if the transduction pathway for this disease affects any other genes, or if there are Anonymousnoreply@blogger.com